Oropharyngeal candidiasis in children with lymphohematopoietic malignancies in Mashhad, Iran
نویسندگان
چکیده مقاله:
Background and Purpose: Over the past years, the role of fungi as a cause of nosocomial infections in hospitalized patients has been accentuated. Candida species constitute an important group of fungi causing diseases in immunocompromised patients. Oropharyngeal candidiasis continues to be a prevalent infection in immunodeficient patients. In this study, we aimed to determine the incidence of oropharyngeal candidiasis in children with lymphohematopoietic malignancies. Materials and Methods: In total, 102 patients with lymphohematopoietic malignancies and 50 healthy controls were examined in terms of Candida infections via direct sampling of the oropharyngeal cavity. Fresh smears were prepared with 10% potassium hydroxide and Gram staining was carried out. Subsequently, the obtained specimens were cultured on Sabouraud dextrose agar for further analysis. Results: The most common Candida species were Candida albicans (31%), other non-C. albicans species (14.7%), C. glabrata (6.8%), and C. krusei (0.98%) in the case group, while in the control group, other non-C. albicans species (10%) and C. albicans (8%) were the most common species. Conclusion: In the present study, Candida species were the most common fungal pathogens in pediatric cancer patients; therefore, efforts should be made to prevent fungemia and fungal pneumonia. Also, non-C. albicans species must be considered as a new risk factor for pediatric cancer patients.
منابع مشابه
oropharyngeal candidiasis in children with lymphohematopoietic malignancies in mashhad, iran
background and purpose: over the past years, the role of fungi as a cause of nosocomial infections in hospitalized patients has been accentuated. candida species constitute an important group of fungi causing diseases in immunocompromised patients. oropharyngeal candidiasis continues to be a prevalent infection in immunodeficient patients. in this study, we aimed to determine the incidence of o...
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چکیده ندارد.
15 صفحه اولOropharyngeal candidiasis in HIV/AIDS patients and non-HIV subjects in the Southeast of Iran
Background and Purpose: Candida species are the common opportunistic pathogens during the course of human immunodeficiency virus (HIV) infection. Oropharyngeal candidiasis (OPC) is generally known as the initial sign of HIV infection. The aim of this study was to compare demographic characteristics and frequency of Candida species between HIV/AIDS patients and non-HIV subjects in Kerman, southe...
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BACKGROUND AND PURPOSE Oropharyngeal candidiasis (OPC) and antifungal drug resistance are major health concerns in patients with human immunodeficiency virus (HIV). The increased reports of antifungal resistance and expanding drug therapy options prompted the determination of antifungal susceptibility profile. The present study was performed to determine the antifungal susceptibility of Candida...
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عنوان ژورنال
دوره 1 شماره None
صفحات 33- 36
تاریخ انتشار 2015-12
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